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Rat Treatment Timeline
LNA-i-miR-221 was administered for 4 consecutive days in two cycles: four administrations on days 1, 2, 3, and 4 for the first cycle, and four administrations on days 15, 16, 17, and 18 for the second cycle (eight administrations in total). A period of 10 days washout between the two cycles was considered. The day of sacrifice was on day 28. Day 1 corresponds to the first day of the treatment period. A recovery period ran from day 29 to day 42.
