Fig. 3.

Pathological features of the kidney in the different treatment groups. A-C: In the Aspirin group, no obvious damage to renal tubule epithelial cells can be seen. D-F: In the Aspirin+Heat group, after 5 h of heat treatment, the renal tubule epithelial cells showed acute degeneration (↑); after 24 h of heat stress, acute degeneration was still the main pathological change, but karyopyknosis (▲) was also observed. G-I: In the Heat group, severe damage to renal tubule epithelial cells can be observed(↑), characterized by disappearance of the nucleus and karyopyknosis (▲) (H&E staining, 400×, 1 bar = 20 μm)