Table 3.
Group parameters | Control | GEN-treated | GEN + NaHS–treated | GEN + NaHS + ZnPP–treated |
---|---|---|---|---|
The mean color area percentage of PAS | 5.06 ± 2.44 | 0.88 ± 0.28 a | 3.33 ± 0.78 ab | 2.28 ± 0.68 ab |
The mean optical density of iNOS immunostaining | 00.00 ± 00.00 | 98.09 ± 2.57 a | 72.51 ± 2.65 abc | 80.19 ± 2.56 abc |
The mean optical density of eNOS immunostaining | 92.08 ± 2.56 | 60.51 ± 6.12 a | 87.02 ± 4.48 ab | 71.54 ± 2.64 abc |
Data represent mean ± SEM of 8 rats
GEN gentamicin, NaHS sodium hydrosulfide, ZnPP zinc protoporphyrin IX, PAS periodic acid Schiff, iNOS inducible nitric oxide synthase, eNOS endothelial nitric oxide synthase
aSignificantly different from the control group
bSignificantly different from the GEN-treated group
cSignificantly different from the GEN + NaHS–treated group (P ˂ 0.05)