Fig. 2.
HSP70 inhibitor VER-155008 can inhibit cell viability in multiple myeloma cell lines. a The chemical structure of VER-155008. b The chemical structure of bortezomib. c RPMI 8226 and MM.1S cells were treated with different doses of VER-155008 between 0 and 20 μM and OPM2 0 and 5 μM. Cell viability was evaluated at 48-h post-treatments by the CCK-8 kit. The half-maximum inhibitory concentration 50 values (IC50 values) were calculated by nonlinear regression in GraphPad Prism version 7.0 software. These experiments were repeated in triplicate