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Apigenin increases the mRNA expression of Nrf2 and its target genes in H2O2-treated human melanocytes. The relative mRNA levels of Nrf2 (a), HO-1 (b), and NQO1(c) were detected by qRT-PCR. Data are presented as mean ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 compared with untreated group; #p < 0.05, ##p < 0.01, ###p < 0.001 compared with H2O2-treated group
