Table 1.
Cluster | Samples (Count) | Median Sum of ROH (Mb) | Median Cumulative IBD (cM) |
---|---|---|---|
Northwest Europe 1 | 11,725 | 2.88 | 15.23 |
Northwest Europe 2 | 1,571 | 2.80 | 15.15 |
Ireland | 2,137 | 2.85 | 15.42 |
Central Europe | 3,116 | 2.83 | 15.06 |
Eastern Europe | 2,471 | 3.16 | 15.37 |
Southern Europe | 1,626 | 2.73 | 14.98 |
Italy | 697 | 6.91 | 14.64 |
Greece-Italy | 238 | 7.28 | 15.02 |
Scandinavia | 717 | 3.02 | 15.54 |
Finland | 314 | 3.67 | 17.50 |
Acadia | 249 | 3.89 | 19.48 |
French Canadian | 314 | 2.89 | 16.60 |
Ashkenazi Jewish | 1,475 | 11.26 | 31.75 |
Admixed Jewish | 445 | 2.75 | 15.50 |
Hispanics/Latinos | 810 | 3.53 | 16.38 |
Hispanics/Latinos in California | 573 | 4.10 | 17.11 |
Hispanics/Latinos in New Mexico | 163 | 5.52 | 21.92 |
Hispanics/Latinos in Texas | 177 | 6.27 | 23.65 |
Puerto Rico | 350 | 8.01 | 26.23 |
African Americans South | 761 | 3.34 | 19.56 |
African Americans North | 420 | 2.94 | 15.90 |
East Asia | 561 | 3.65 | 19.63 |
Southeast Asia | 325 | 8.44 | 17.90 |
South Asia | 389 | 10.42 | 14.82 |
Greater Middle East | 93 | 9.01 | 17.16 |
Sum of runs of homozygosity (sROH) was calculated by summing the lengths of continuous homozygous segments ≥1 Mb. Cumulative IBD was determined by summing IBD segments of ≥3 cM and filtering for only pairs ≥12 cM and ≤72 cM. Statistics were determined within haplotype clusters, rather than across the ancestrally heterogeneous and imbalanced full network.