Table 2.

Factors associated with overall and disease-free survival on univariate analysis for patients who underwent first repeat metastasectomy after hepatectomy for CLM.

Variable	Overall survival			Disease-free survival
	5-y OS	Median OS	P	5-y DFS	Median DFS	P
	(%)	(month)		(%)	(month)
Age
70 or <70 years old	49	59	0.36	35	23	0.48
70 years old<	50	60<		NA	37
Gender
Female	73	60<	0.11	24	18	0.35
Male	38	53		31	31
Depth of primary tumor
T1-T3	60	60<	0.054	37	31	0.053
T4	15	47		NA	9
Lymph node metastases of primary tumor
N0	34	38	0.24	NA	17	0.012
N1<	53	60<		38	31
Right side primary (Cecum-Transverse colon)
Right	27	34	0.023	20	9	0.057
Left-rectum	54	60<		31	26
Chemotherapy before initial hepatectomy
Yes	63	60<	0.36	17	22	0.40
No	43	53		35	24
Chemotherapy after initial hepatectomy
Yes	60	60<	0.028	30	26	0.59
No	16	43		30	21
Chemotherapy after repeat metastasectomy
Yes	59	60<	0.26	27	22	0.72
No	37	53		32	26
DFI (Primary resection to initial hepatectomy)
<12 months	49	56	0.67	28	22	0.29
12 months<	51	60<		36	37
DFI (Initial hepatectomy to repeat metstasectomy)
<12 months	28	46	.0057	11	20	0.011
12 months<	77	60<		58	60<
Extra-hepatic metastases at initial hepatectomy
Present	20	43	0.042	0	19	0.13
No	56	60<		36	26
CEA level at initial hepatectomy
<20 ng/ml	52	60<	0.67	18	22	0.23
20 ng/ml<	43	54		41	40
Nunmer of metastases at repaet metastasectomy
1	53	60<	0.36	33	31	0.73
2 or more	42	56		22	22
Type of metastasectomy
Hepatectomy only	52	60<	0.17	38	31	0.37
Lung resection only	34	43		26	15
Others	72	60<		20	26

OS overall survival, DFS disease free survival, NA not assessed.