Table 1.

Descriptive statistics of demographic and hormone data by sex. All change values reported were scaled by interval. Numbers in brackets indicate number of participants missing values for a specific measurement.

	Males (M ± SD, range) [# missing]	Females (M ± SD, range) [# missing]
Age at Time 1 (years)	11.90 ± 1.02 (10.08–14.17)	11.14 ± 1.05 (9.25–13.75)
Age at Time 2 (years)	13.88 ± 1.12 (11.92–16.50)	12.93 ± 1.32 (9.67–15.75)
Interval (years)	1.98 ± 0.33 (1.42–2.84)	1.80 ± 0.62 (0.42–3.41)
Ethnicity (% Caucasian)	62.1 %	56.9 %
Menarche (% by Time 2)	N/A	63.3 % [2]
Days Since Last Period	N/A	11.62 ± 12.7 (1–47) [5]
Corticosteroid Usage	4	4
Tanner Average (Time 1)	2.05 ± 0.91 (1.0–5.0)	2.09 ± 0.79 (1.0–3.5)
Tanner Average (Time 2)	3.55 ± 0.89 (2.0–5.0) [1]	3.28 ± 0.95 (1.0–5) [1]
Tanner Change	0.85 ± 0.40 (0–1.52) [1]	0.64 ± 0.50 (−1.33 – 1.47) [1]
Time of Saliva Collection at Time 1 (hours after midnight)	8.12 ± 1.73 (5–14.42)	7.36 ± 1.06 (5.5–9.75)
Time of Saliva Collection at Time 2 (hours after midnight)	8.00 ± 1.86 (3.58–14.42)	8.2 ± 1.14 (5.12–10.67)
Estradiol at Time 1 (pg/mL)	N/A	1.01 ± 0.48 (0.26–2.06) [3]
Estradiol at Time 2 (pg/mL)	N/A	1.11 ± 0.51 (0.24–2.22) [3]
Change in Estradiol (pg/mL)	N/A	0.14 ± 0.64 (−1.36 – 1.80) [6]
Transformed Estradiol at Time 1 (ln)	N/A	−0.12 ± 0.53 (−1.35 – 0.72) [3]
Transformed Estradiol at Time 2 (ln)	N/A	−0.02 ± 0.54 (−1.43 – 0.8) [3]
Change in Transformed Estradiol (ln/year)	N/A	0.01 ± 0.45 (−1.56 – 0.9) [6]
Testosterone at Time 1 (pg/mL)	70.44 ± 55.33 (18.29–300.16)	51.92 ± 19.67 (16.27–112.56)
Testosterone at Time 2 (pg/mL)	130.02 ± 71.15 (18.29–300.16)	57.68 ± 28.25 (20.92–147.09)
Change in Testosterone (pg/mL/year)	59.58 ± 71.54 (−103.71–299.51)	5.76 ± 27.4 (−66.47–92.49)
Log Transformed Testosterone at Time 1 (ln)	4.07 ± 0.58 (2.91–5.7)	3.88 ± 0.38 (2.79–4.72)
Log Transformed Testosterone at Time 2 (ln)	4.72 ± 0.58 (3.04–5.84)	3.95 ± 0.44 (3.04–4.99)
Change in Transformed Testosterone (ln/year)	0.66 ± 0.54 (−0.42 – 2.08)	0.07 ± 0.44 (0.96–1.12)