Table 2.

Duration of drug therapy.

Society/agency	Treatment duration	Comments
Infectious Disease Society of America/American Thoracic Society/Centers for Disease Control and Prevention (CDC) combined guidelines for drug susceptible TB (2016)	6–9 months	Experts favor 9 months citing difficulty in assessing treatment response. In the setting of orthopedic hardware, an extension of treatment up to 12 months has also been recommended, though these guidelines acknowledge that there is a wider range on expert opinion on length of treatment for extrapulmonary sites including bone [37].
World Health Organization (2017)	9 months	Duration longer than that for pulmonary TB citing the difficulty in monitoring treatment response.
National Institute for Health and Care Excellence (NICE, United Kingdom, 2016)	Without central nervous system involvement: 6 months With CNS involvement or patients with coexisting HIV: 9 months [67].