TABLE 2.

Univariate and multivariate analyses of the characteristics associated with OS in 203 cervical carcinoma patients.

Characteristics	Univariate			Multivariate
	HR	95% CI	p-value	HR	95% CI	p-value
Age, years	0.818	0.530–1.263	0.365	0.741	0.478–1.150	0.181
Histologic type
AD/ASC	1.00 (ref.)			1.00 (ref.)
SCC	1.256	0.706–2.234	0.438	1.301	0.709–2.387	0.395
FIGO stage
I–II	1.00 (ref.)			1.00 (ref.)
III–IV	2.490	1.588–3.905	<0.001	1.782	1.060–2.995	0.029
Histologic grade
G1-G2	1.00 (ref.)			1.00 (ref.)
G3	1.575	1.018–2.436	0.041	1.313	0.835–2.064	0.239
Lymph node metastasis
No	1.00 (ref.)			1.00 (ref.)
Yes	3.341	2.115–5.276	<0.001	1.887	1.083–3.287	0.025
Snail expression
Low	1.00 (ref.)			1.00 (ref.)
High	2.238	1.366–3.668	0.001	1.744	1.038–2.928	0.036
Slug expression
Low	1.00 (ref.)			1.00 (ref.)
High	1.785	1.133–2.813	0.012	0.727	0.410–1.288	0.274
ZEB1 expression
Low	1.00 (ref.)			1.00 (ref.)
High	1.181	0.765–1.822	0.128	1.239	0.749–2.051	0.404
Twist expression
Low	1.00 (ref.)			1.00 (ref.)
High	2.131	1.341–3.386	0.001	0.926	0.434–1.980	0.844
Vimentin expression
Low	1.00 (ref.)			1.00 (ref.)
High	2.226	1.387–3.573	0.001	1.467	0.828–2.599	0.189
Survivin expression
Low	1.00 (ref.)			1.00 (ref.)
High	1.791	1.135–2.827	0.012	1.348	0.737–2.465	0.332
E-cadherin expression
Low	1.00 (ref.)			1.00 (ref.)
High	2.612	1.583–4.309	<0.001	1.738	1.008–2.998	0.047

AD, adenocarcinoma; ASC, adenosquamous cell carcinoma; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio; SCC, squamous cell carcinoma. Bold font indicates p-values < 0.05.