Table 2.

Top significantly enriched predicted microbial KEGG functions for clownfish hosting (grey highlighted) and non-clownfish host sea anemones. Positive log-2-fold-change values indicate microbial functions enriched in host versus non-host anemones.

KEGG function	log-2-fold-change	p-adj	clownfish association
ARA metabolism	25.841	2.57 × 10−12	host
protein digestion and absorption	2.100	9.71 × 10−10	host
renin–angiotensin system	1.903	0.040	host
non-homologous end-joining	1.730	0.007	host
lysosome	1.543	0.002	host
phosphonate and phosphinate metabolism	1.534	1.19 × 10−7	host
linoleic acid metabolism	1.527	1.96 × 10−9	host
flavonoid biosynthesis	1.516	0.006	host
penicillin and cephalosporin biosynthesis	1.431	9.71 × 10−10	host
primary bile acid biosynthesis	1.422	0.001	host
RNA polymerase	−0.608	1.19 × 10−6	non-host
flagellar assembly	−0.645	0.005	non-host
d-alanine metabolism	−0.711	2.00 × 10−6	non-host
biosynthesis of ansamycins	−0.740	5.29 × 10−6	non-host
insulin signalling pathway	−0.803	2.95 × 10−6	non-host
d-arginine and d-ornithine metabolism	−1.029	0.0008	non-host
amoebiasis	−1.355	0.0003	non-host
proteasome	−1.431	0.0178	non-host
systemic lupus erythematosus	−1.798	0.0107	non-host
cell adhesion molecules	−2.909	0.0017	non-host