Skip to main content
. 2020 Feb 28;8:73. doi: 10.3389/fchem.2020.00073

Table 7.

Inhibitory effects of positive control and 113 on NO production in RAW 264.7 cells.

No. NRC (%) No. NRC (%) No. NRC (%)
Normal 1.5 ± 0.5 4 102.2 ± 3.1 10 91.5 ± 2.6**
Control 100.0 ± 3.3 5 73.3 ± 2.6*** 11 56.5 ± 3.5***
DEX 71.8 ± 0.9*** 6 103.8 ± 3.0 12 97.4 ± 1.1
1 101.6 ± 3.7 7 90.4 ± 2.6** 13 10.5 ± 0.3***
2 99.2 ± 1.9 8 90.2 ± 0.7**
3 99.9 ± 2.3 9 92.2 ± 2.4**

N, Unstimulated normal (negative control); C, Control group (stimulated by LPS); D, Dexamethasone (Dex, a positive control). Nitrite relative concentration (NRC): percentage of control group, which set as 100%. Values represent the mean ± SD of three determinations.

**

P < 0.01;

***

P < 0.001 (differences between the compound-treated group and the control group). n = 4. Final concentration was 20 μM for 113, and 1 μg/ml for Dex, respectively.