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. 2019 Nov 14;9(9):692–702. doi: 10.1089/brain.2019.0692

FIG. 2.

FIG. 2.

(A) Cerebral cortical results from between-group seed-to-voxel RsFc analysis for HC > ASD contrast (two-sided) for right DN at a height threshold of whole brain, p < 0.001 (T = 3.57), and FDR-corrected cluster threshold of p < 0.05. Age was added as a regressor of no interest. (B) Cerebellar results of the same contrast presented in a cerebellar flat map (Diedrichsen and Zotow, 2015). Cluster labels in (A) and (B) correspond to Table 2. (C) Cerebellar cluster shown in (B) overlaid on cerebellar representations of cerebral cortical networks (Buckner et al., 2011): dark purple, visual; blue, somatomotor; green, dorsal attention; violet, ventral attention; cream, limbic; orange, frontoparietal; and red, default network. (D) Cerebellar cluster shown in (B) represented in the functional gradient space as developed by Guell and colleagues (2018c). Each dot represents one cerebellar voxel; dots shown in color correspond to the voxels that are included in the cerebellar cluster shown in (B). (E) HC within-group connectivity from the right DN seed at a height threshold of whole brain, p < 0.001, and FDR-corrected cluster threshold of p < 0.05. (F) ASD within-group connectivity from the right DN seed using the same thresholds as in (E). (G) Boxplots of ASD and HC connectivity data extracted from clusters shown in (A) and (B). HCs, healthy controls; ASD, autism spectrum disorder; FDR, false discovery rate; RsFc, resting-state functional connectivity. Color images are available online.