FIG. 5.

(A) AFSC-injected kidneys showed fine interstitium in the cortex area and thin basement membrane in the glomerulus, similar to the sham group. However, vehicle group kidneys contained sclerotic glomerulus (yellow arrowhead) and a thick basement membrane (black arrowheads). (B) Glomerular damage was quantified by basement membrane thickness (b). (C) Distance between the glomerulus and the basement membrane (d). (D) Internal radius of Bowman's capsule (r). (E) Quantitative analysis of glomerulosclerosis. (F) Quantitative analysis of tubular damage score. Each data point is a mean ± SD of 12 values. *Statistical significance (p < 0.01) compared with PBS-treated group. Periodic acid-Schiff's staining. Scale bar = 20 μm. Color images are available online.