Figure 7.

Effect of J. Regia and Mangifera Indica aqueous extracts (250 µg/mL) on the cytochrome c release in the lymphocyte mitochondria isolated from CLL patients’ group. As shown in this figure, only addition of Mangifera Indica aqueous extracts (250 µg/mL) induced cytochrome c release in cancerous BUT NOT normal mitochondria, also pretreatment of BHT or Cs.A significantly prevented cytochrome c release in the cancerous lymphocyte mitochondria. The amount of expelled cytochrome c from mitochondrial fraction into the suspension buffer was determined by man Cytochrome c ELISA kit.

Values presented as mean ± SD of five separate experiments (n = 5).

***: Significant difference in comparison with CLL untreated control (p < 0.001).

###: Significant difference in comparison with CLL Mangifera Indica group (p < 0.001). ns indicates non-significant with control