Table 2.

Details of clonidine effects on sedative total doses, duration of ventilation, and PICU stay

	Placebo (n = 50)	Intervention (n = 46)	P value
Clonidine total dose (µg)	0	39.9 ± 14.9	0.4
Midazolam total dose (mg)	4.3 ± 2.2	2.7 ± 2.9	<0.05
Fentanyl total dose (µg)	34.4 ± 23.1	18.9 ± 10	<0.01
Duration of infusion (hr)	53 ± 4.9	56 ± 9.9	0.9
Ramsay score (baseline)	1.1± 0.2	1 ± 0.1	0.3
Ramsay score (during study)	2.6 ± 0.9	2.6 ± 1	0.7
Time at target sedation (%)	68	71	0.4
Duration of ventilation (day)	7.1 ± 1.1	6.3 ± 1.7	0.8
Length of PICU stay (hr)	198 ± 21	210 ± 19	0.7

Data are shown in number or mean ± SD.