Table 4.

Cytotoxicity (% of viability) of methanol extract of medicinal plants from Chaharmahal and Bakhtiari Province of Iran

	Concentration1
Cell line→	PC3			MCF7			HepG2			CHO			B16-F10
Plant name↓	0	50	100	0	50	100	0	50	100	0	50	100	0	50	100
Achillea kellalensis	100.0±19.3	107.0±29.0	104.3±33.2	100.0±39.7	99.7±27.6	110.2±45.5	99.9±13.5	87.5±12.9	93.6±10.5	100.0±39.3	72.1±23.5	77.7±19.5	100.0±7.0	110.6±8.4	88.7±19.1
Ajuga chamaecistus	100.0±19.3	105.4±33.3	100.8±41.5	100.0±39.7	105.9±31.5	96.8±38.8	99.9±13.5	103.5±9.3	98.0±11.3	100.0±39.3	66.7±15.7	54.0±8.9	100.0±7.0	102.0±15.2	99.9±8.9
Aristolochia olivieri	100.0±19.3	105.7±21.0	111.0±19.7	100.0±39.7	111.3±9.8	121.4±5.6	99.9±13.5	108.1±9.2	112.0±6.1	100.0±39.3	90.1±20.6	79.2±30.6	100.0±7.0	98.5±13.8	108.8±45.1
Cicer oxyodon	100.0±19.3	107.7±39.5	101.5±22.9	100.0±39.7	101.0±36.3	96.8±37.5	99.9±13.5	113.0±6.6	120.6±8.4	100.0±39.3	63.3±20.7*	68.5±28.2*	100.0±7.0	81.0±7.8	71.7±10.1
Dianthus orientalis	100.0±19.3	107.6±22.7	105.8±23.6	100.0±39.7	104.9±26.1	97.5±39.2	99.9±13.5	89.4±9.5	95.4±10.9	100.0±39.3	73.4±23.0	79.7±24.6	100.0±7.0	81.0±30.6	102.3±18.4
Dionysia sawyeri	100.0±19.3	95.3±27.8	98.6±29.0	100.0±39.7	91.2±13.7	104.6±14.4	99.9±13.5	93.0±7.2	87.3±6.0	100.0±39.3	62.3±16.8*	58.6±19.7*	100.0±7.0	76.5±21.3*	62.9±12.8*
Doxorubicin	100.0±19.3	58.6±18.7*	46.6±17.1*	100.0±39.7	36.4±26.8**	52.7±21.1*	99.9±13.5	38.8±15.2**	40.0±15.2*	100.0±39.3	64.8±26.3*	71.2±15.7*	100.0±7.0	20.4±12.5**	36.2±11.7**
Linum album	100.0±19.3	110.8±20.7	100.9±15.1	100.0±39.7	120.3±21.4	120.0±13.3	99.9±13.5	96.2±10.2	97.7±13.6	100.0±39.3	88.1±16.8	74.7±11.7	100.0±7.0	63.6±6.8*	69.6±20.1*
Nepeta glomerulosa	100.0±19.3	102.4±20.4	106.1±19.5	100.0±39.7	125.9±13.7	117.8±12.9	99.9±13.5	96.7±10.3	101.5±8.0	100.0±39.3	88.9±29.4	86.5±28.3	100.0±7.0	102.5±10.4	111.8±13.8
Phlomis aucheri	100.0±19.3	103.8±27.0	97.8±12.8	100.0±39.7	112.7±12.5	116.7±16.6	99.9±13.5	89.7±10.0	97.6±11.2	100.0±39.3	98.2±19.9	75.8±24.6	100.0±7.0	104.0±16.9	96.3±21.0
Picris strigosa	100.0±19.3	106.4±23.0	104.5±36.0	100.0±39.7	114.0±11.1	112.0±11.1	99.9±13.5	102.5±8.9	105.1±5.9	100.0±39.3	70.8±17.8	76.0±18.4	100.0±7.0	114.5±9.5	92.9±21.9
Scutellaria multicaulis	100.0±19.3	96.8±25.2	96.7±36.1	100.0±39.7	104.8±26.1	91.9±5.8	99.9±13.5	92.5±8.6	94.8±4.2	100.0±39.3	58.5±43.9	72.6±42.0	100.0±7.0	89.3±16.5	79.5±20.8
Stachys obtusicrena	100.0±19.3	120.2±18.2	98.3±21.0	100.0±39.7	102.8±25.7	109.8±10.4	99.9±13.5	90.2±12.8	87.5±5.3	100.0±39.3	61.1±20.0*	53.7±6.3*	100.0±7.0	86.7±21.3	98.7±17.7
Tanacetum dumosum	100.0±19.3	91.6±29.8	92.2±28.2	100.0±39.7	79.3±35.4	100.0±14.8	99.9±13.5	99.7±7.8	112.3±8.3	100.0±39.3	89.9±29.8	78.8±32.3	100.0±7.0	87.0±25.9	74.2±38.2

¹ The concentration of extracts is presented in µg/mL.

Dunnet's Multiple Comparison Test;*p < 0.05, **p < 0.001