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Loading content and encapsulation efficiency of gemcitabine and (or) SPION. Encapsulation efficiency of SPION and gemcitabine were determined in triplicate using atomic absorption spectrophotometer and UV-Vis spectrophotometer, respectively
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Encapsulation efficiency (%)
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Loading content (%)
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|---|---|---|---|---|
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Formulation
| ||||
| Gem | SPION | Gem | SPION | |
| PLGA-SPION | - | 50.1 ± 1.1 | - | 28.6 |
| PLGA-Gem | 13.2 ± 1.3 | - | 3. 8 | - |
| PLGA-SPION-Gem | 16.1 ± 2.2 | 48.2 ± 2.1 | 2.8 | 27.8 |
