Table 4.
Correlation coefficient (R2) obtained from curve fitting of imatinib release data from optimized LNC
Formulation |
Kinetic models (r2)
|
Korsmeier-Peppas parameters
|
|||||
---|---|---|---|---|---|---|---|
Baker- Lonasdale | Higuchi | Hixon- Crowel | First order | Zero order | n | r 2 | |
S15 O10W2.5 | 0.9975 | 0.9747 | 0.7454 | 0.9818 | 0.8802 | 0.4385 | 0.9793 |
S: Surfactant%; O: Oil phase%; W: Volume ratio of the diluting aqueous phase to the initial emulsion.