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Size, Zeta potential, PDI, mRNA encapsulation efficiency (EE) and loading capacity (LC) of mRNA-loaded nanoparticle
| Formulation | Size (nm) | PDI a | Zeta Potential (mV) | EE (%) b | LC (%) c |
|---|---|---|---|---|---|
| Blank PLGA/PEI NPs | 428 ± 12 | 0.437 ± 0.012 | 12.9 ± 0.275 | - | - |
| mRNA encapsulated PLGA/PEI NPs | 606 ± 9.7 | 0.454 ± 0.084 | 12.2 ± 0372 | 73.54 ± 2.12 | 11.47 ± 0.33 |
aPolydispersity Index. bEncapsulation Efficiency. cLoading Capacity.
