TABLE 2.
Regulation and function of quantified proteins involved in respiration.
Protein | Function | Regulation | -LOG(P-value) | Difference |
CccA | Cytochrome c550 | ↓ | 1.29 | –0.25 |
CccB | Cytochrome c551 | = | 0.38 | –0.07 |
CtaC | Cytochrome-c oxidase (subunit II) | ↓ | 4.07 | –0.76 |
CtaD | Cytochrome-c oxidase (subunit I) | ↓ | 3.52 | –0.77 |
CtaE | Cytochrome-c oxidase (subunit III) | ↓ | 3.07 | –0.65 |
CtaF | Cytochrome-c oxidase (subunit IV) | ↓ | 3.24 | –0.84 |
CtaG | Formation of functional cytochrome C-oxidase (caa3) | ↓ | 3.04 | –0.71 |
CydA | Cytochrome bd ubiquinol oxidase (subunit I) | ↓ | 3.28 | –0.87 |
CydB | Cytochrome bd ubiquinol oxidase (subunit II) | ↓ | 3.52 | –0.82 |
CydC | ABC transporter required for expression of cytochrome bd | ↓ | 3.81 | –0.97 |
CydD | ABC transporter required for expression of cytochrome bd | ↓ | 3.18 | –0.71 |
NarG | Nitrate reductase (α subunit) | OFF | ||
NarH | Nitrate reductase (β subunit) | OFF | ||
NarI | Nitrate reductase (γ subunit) | OFF | ||
NarK | Nitrite extrusion protein | OFF | ||
Ndh | NADH dehydrogenase | ↑ | 2.31 | 0.31 |
QcrA | Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit) | ↓ | 2.97 | –0.49 |
QcrB | Menaquinol:cytochrome c oxidoreductase (cytochrome b subunit) | ↓ | 2.23 | –0.27 |
QcrC | Menaquinol:cytochrome c oxidoreductase (cytochrome b/c subunit) | ↓ | 2.72 | –0.29 |
QoxA | Cytochrome aa3 quinol oxidase (subunit II) | = | 0.62 | –0.05 |
QoxB | Cytochrome aa3 quinol oxidase (subunit I) | = | 0.29 | –0.05 |
QoxD | Cytochrome aa3 quinol oxidase (subunit IV) | = | 0.57 | 0.17 |
QoxD | Cytochrome aa3 quinol oxidase (subunit III) | = | 0.04 | 0.03 |
ResA | Cytochrome c biogenesis | ↓ | 3.42 | –0.26 |
ResB | Cytochrome c biogenesis | ↓ | 2.90 | –0.25 |
ResC | Cytochrome c biogenesis | ↓ | 1.83 | –0.25 |
Sco | Maturation of cytochrome c oxidase caa3 | ↓ | 2.77 | –0.37 |
YojN | Unknown | ↑ | 3.39 | 0.39 |
Absolute amounts for all quantified proteins and regulation of significantly changed abundances can be found in Supplementary Tables S5, S6, respectively.