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. 2020 Feb 14;19(3):e13113. doi: 10.1111/acel.13113

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© 2020 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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TRPV1 interacts with GluA2 subunit of AMPAR. (a and b) Immunoprecipitation (IP) of hippocampal samples from WT and APP23/PS45 mice after extraction in lysis buffer with antibodies to TRPV1 or negative control antibodies (IgG) and immunoblot analysis with the indicated antibodies to the TRPV1, GluA1 (a), and GluA2 (b). (c and d) IP of hippocampal samples from WT and APP23/PS45 mice after extraction in lysis buffer with antibodies to GluA1, GluA2, or IgG and immunoblot analysis with the indicated antibodies to the TRPV1, GluA1 (c), and GluA2 (d)