Figure 6.

Capsaicin rescues learning and memory deficits in APP23/PS45 mice. (a) The escape latency to the hidden platform during spatial learning in the Morris water maze paradigm (n = 7–10 in each group). Repeated measures ANOVA: F _(5,42) = 6.274, p < .001. (b) The number of entries into the platform zone. One‐way ANOVA: F _(5,42) = 4.276, p = .003. (c) The latency to the escape box during spatial learning in the Barnes maze paradigm (n = 5–8 in each group). Repeated measures ANOVA: F _(5,37) = 8.805, p < .001. (d) The occurrence of head dips to the escape hole during memory retrieval. One‐way ANOVA: F _(5,37) = 5.024, p = .001. Data are expressed as mean ± SEM, *p < .05, **p < .01