Figure 1.

Aging alters plasma EV‐like particle concentration and size. (a) Size exclusion chromatography isolation of plasma EV enriched fractions from young (top) and old (bottom) plasma. (b) Representative transmission electron microscopy (TEM) images of particles isolated from young and old plasma. (c) Quantification of particle size distribution in 25 nm bins from TEM images, n = 3/group. (d) Representative Western blots images and (e) quantification, n = 4/group, *p < .05. All values are mean ± SEM