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Young‐donor hematopoietic stem cells (HSCs) extend the lifespan of aged female recipients. Survival of wild‐type, female mice (19‐month‐old) receiving mobilization‐based conditioning followed by infusion of either young‐donor (2‐month‐old) HSCs (young to old, blue) or PBS (mobilized control, red) were compared with aged, wild‐type, female nonmobilized control (black). young to old, N = 42; mobilized control, N = 44; nonmobilized control, N = 58
