Figure 5.

Schematic illustration comparing mechanisms between conventional and mobilization‐based hematopoietic stem cell transplantation (HSCT). First column depicts conventional HSCT following irradiation or chemotherapeutic conditioning, allowing noncompetitive engraftment of donor hematopoietic stem cells (HSCs), but significant damage to the stroma. Second column depicts HSCT following mobilization‐based conditioning, allowing infusion of superior donor HSC populations to out‐compete endogenous cells for limited niche spaces, while preserving the stroma