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. 2020 Feb 28;7:74. doi: 10.3389/fmed.2020.00074

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Copyright © 2020 Lu, Wei, Chang, Chen, Tsai and Yeh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intra-articular tophi evaluation and response assessment. (A) Baseline MRI of the knee joint of a 31-year-old man with subcutaneous tophaceous gout revealed multiple intra-articular tophi. A tophus within the knee joint was measured according to response evaluation criteria in solid tumors criteria. The total length in this plane is the sum of a + b + c + d, 17.23 cm. (B) Follow-up MRI revealed decreased intra-articular tophi size. The tophi at a and c dissolved, and those at b and d decreased.