Table 1.

Clinical features of 26 patients with tophaceous gout and limited knee-joint range of motion.

Characteristics	Before ULT	After ULT	P-value
			Paired t-test	t-test
Male sex, n (%)	26 (100%)
Presence of intra-articular tophi, n (%)	26 (100%)
Subcutaneous tophi over knee, n (%)	16 (61.5%)
Age at initial visit (yr)	48.4 ± 9.8
Age at gout onset (yr)	33.2 ± 10.2
Age of tophi onset (yr)	40.3 ± 9.9
Subcutaneous tophi duration (yr)	8.7 ± 6.2
Difficulty in squatting (yr), n = 23	4.7 ± 3.7
Total subcutaneous tophi (cm)	52.8 ± 40.5	8.1 ± 12.5	<0.001	<0.001
Total intra-articular tophi (cm)	18.0 ± 9.5	8.2 ± 4.7	<0.001	<0.001
Knee joint range of motion (degree)	103.5 ± 5.7	129.6 ± 6.5	<0.001	<0.001

Comparison before and 18.2 months (standard deviation [SD]: 5.9 months) after urate-lowering therapy (ULT).

Data are expressed as mean ± standard deviation or number (percentage), p < 0.05 considered significant.