Wilkinson 1985.

Methods	Randomized Single Center Blinding of randomization: yes (sealed envelopes) Blinding of intervention: yes Complete follow‐up: yes Blinding of outcome measurement: yes Stratification based on gender
Participants	Premature infants Gestational age < 31 weeks Intubated in delivery room Infants randomized: DPPC/PG = 16 Control = 16
Interventions	Intratracheal administration of dry powdered dipalmitoylphosphatidylcholine and phosphatidylglycerol vs. routine resuscitation
Outcomes	Requirement for respiratory support Complications of respiratory distress syndrome Follow‐up : for a minimum 2 years
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Stratification based on gender
Allocation concealment?	Low risk	Blinding of randomization: yes (sealed envelopes)
Blinding? All outcomes	Low risk	Blinding of intervention: yes Blinding of outcome measurement: yes
Incomplete outcome data addressed? All outcomes	Low risk	Complete follow‐up: yes
Free of selective reporting?	Low risk
Free of other bias?	Low risk