Figure 4.

Phasic and tonic inhibitory transmission in CRF1 lateral amygdala neurons. A, Representative voltage-clamp recording of a CRF1⁺ cell (left) and a CRF1⁻ cell (right). B, Summary of sIPSC frequency (left), amplitude (center), and decay (right) of CRF1⁺ and CRF1⁻ cells. *p < 0.05 by unpaired t test comparing CRF1⁺ to CRF1− cells. C, Representative voltage-clamp recording of a CRF1⁺ cell (left) and a CRF1⁻ cell (right) during GBZ superfusion (100 μm). White dashed line indicates level of holding current before and after GBZ superfusion. D, Summary of the tonic current revealed by gabazine. *p < 0.05 by unpaired t test comparing CRF1⁺ to CRF1⁻ cells. E, Summary of the change in rms noise induced by gabazine superfusion in CRF1⁺ (left) and CRF1⁻ (right) cells.