Table 1.
Baseline characteristics of patients in the CCRT and CCRT + IC groups.
| Characteristic | CCRT n (%) | CCRT + IC n (%) | P-value |
|---|---|---|---|
| Total | 2,077 | 1,509 | |
| Age, y | |||
| ≤ 46 | 1,009 (48.6) | 769 (51.0) | 0.166 |
| >46 | 1,068 (51.4) | 740 (49.0) | |
| Gender | |||
| Female | 552 (26.6) | 354 (23.5) | 0.036 |
| Male | 1,525 (73.4) | 1,155 (76.5) | |
| Diabetes mellitus | |||
| No | 2,014 (97.0) | 1,480 (98.1) | 0.042 |
| Yes | 63 (3.0) | 29 (1.9) | |
| Cardiovascular disease | |||
| No | 1,957 (94.2) | 1,431 (94.8) | 0.459 |
| Yes | 120 (5.8) | 78 (5.2) | |
| T stagea | |||
| T1 | 69 (3.3) | 45 (3.0) | <0.001 |
| T2 | 232 (11.2) | 181 (12.0) | |
| T3 | 1,365 (65.7) | 740 (49.0) | |
| T4 | 411 (19.8) | 543 (36.0) | |
| N stagea | |||
| N0 | 328 (15.8) | 135 (8.9) | <0.001 |
| N1 | 759 (36.5) | 433 (28.7) | |
| N2 | 967 (41.7) | 710 (47.1) | |
| N3 | 123 (5.9) | 231 (15.3) | |
| LDH level | |||
| ≤ 245 U/L | 1,981 (95.4) | 1,399 (92.7) | 0.001 |
| >245 U/L | 96 (4.6) | 110 (7.3) | |
| EBV DNA level | |||
| ≤ 1,500 copies/ml | 913 (44.0) | 425 (28.2) | <0.001 |
| >1,500 copies/ml | 1,164 (56.0) | 1,084 (71.8) | |
CCRT, concurrent chemoradiotherapy; IC, induction chemotherapy; LDH, lactate dehydrogenase; EBV, Epstein–Barr virus.
a
According to the 8th edition of the UICC/AJCC staging system.
P-values were calculated by a χ2-test.