Table 6.
Acute toxicities in patients between CCRT and CCRT + IC groups.
| Adverse event (Toxicity grade) | CCRT (n = 2,077) | CCRT + IC (n = 1,509) | P-value | ||
|---|---|---|---|---|---|
| 0–2 (%) | 3–4 (%) | 0–2 (%) | 3–4 (%) | ||
| Leukocytopenia | 1,738 (83.7) | 339 (16.3) | 1,056 (70.0) | 453 (30.0) | <0.001 |
| Neutropenia | 1,761 (84.8) | 316 (15.2) | 939 (62.2) | 570 (37.8) | <0.001 |
| Anemia | 2,033 (97.9) | 44 (2.1) | 1,481 (98.2) | 28 (1.8) | 0.631 |
| Thrombocytopenia | 2,052 (98.8) | 25 (1.2) | 1,484 (98.3) | 25 (1.7) | 0.313 |
| Hepatoxicity | 2,054 (98.9) | 23 (1.1) | 1,482 (98.2) | 27 (1.8) | 0.112 |
| Nephrotoxicity | 2,077 (100.0) | 0 (0.0) | 1,507 (99.9) | 2 (0.1) | 0.177a |
CCRT, concurrent chemoradiotherapy; IC, induction chemotherapy.
a
P-value was calculated with the Pearson χ2-test or Fisher's exact test.