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. 2020 Feb 28;10:261. doi: 10.3389/fonc.2020.00261

Figure 4.

Figure 4

Forest plots for the risk ratio of hepatitis for grade 3–5. (A) Forest plots for the risk ratio of treatment related hepatitis (PD-1/PD-L1 vs. Docetaxel/Paclitaxel or Chemotherapy). Subgroup analysis was performed according to the composition of chemotherapy in the control group. (B) Forest plots for the risk ratio of treatment related hepatitis (PD-1/PD-L1 + Chemotherapy vs. Chemotherapy). Subgroup analysis was performed based on the drug type (PD-1 or PD-L1) of the experimental group. (C) Forest plots for the risk ratio of treatment related hepatitis (PD-1 vs. Placebo). (D) Forest plots for the risk ratio of treatment related hepatitis (Nivolumab + Ipilimumab vs. Ipilimumab). (E) Forest plots for the risk ratio of treatment related hepatitis (Nivolumab + Ipilimumab vs. Nivolumab).