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. 2020 Mar 5;13:13. doi: 10.1186/s13072-020-00332-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — DNE does not impact TET2 content in the frontal cortices, striata, or hippocampi. Representative Western blot images and densitometric measurements of TET2 abundance in frontal cortices (n_F1Veh = 7, n_F1NIC = 8, and n_F2NIC = 10), striata (n_F1Veh = 7, n_F1NIC = 9, and n_F2NIC = 9), and hippocampi (n_F1Veh = 8, n_F1NIC = 9, and n_F2NIC = 8). a TET2 abundance in frontal cortices. Frontal cortical TET2 content is unaltered in F1 NIC and F2 NIC mice. b TET2 abundance in striata. Striatal TET2 content is unaltered in F1 NIC and F2 NIC mice. c TET2 abundance in hippocampi. Hippocampal TET2 content is unaltered in F1 NIC and F2 NIC mice. FCX frontal cortices, STR striata, HIPP hippocampi, TET2 ten-eleven translocase methylcytosine dioxygenase 2, TET2 (1) TET2 isoform 1, TET2 (2) TET2 isoform 2, TET2 (3) TET2 isoform 3, TBP TATA-binding protein. All data are mean ± SEM