Table 1.

The mean values of eight simple descriptors for inhibitors and non-inhibitors and the associated p-values determined by Mann–Whitney U-test for each descriptor

Class	SlogP	logS	a_acc	a_don	b_rotN	KierFlex	a_aro	b_ar
Inhibitors	4.26	− 6.07	4.10	1.19	6.09	4.36	17.51	18.01
Non-inhibitors	3.29	− 5.25	3.70	1.41	5.88	4.53	13.46	13.73
p-value	2.16 × 10−50	4.63 × 10−27	1.32 × 10−09	1.12 × 10−08	6.38 × 10−01	3.14 × 10−04	6.90 × 10−75	5.90 × 10−80