Table 4.
Accuracy of different variables in predicting weaning failure
| Parameter | AUC (95% CI) | Sensitivity | Specificity | PPV | NPV | Cutoff value |
|---|---|---|---|---|---|---|
| TFC | 0.69(0.57–0.80)* | 65.2% | 75.6% | 60.0% | 79.5% | > 50 kΩ−1 |
| Serum HCO3 | 0.60 (0.47–0.72) | 56.5% | 68.3% | 50.0% | 73.7% | > 25 mmol.L−1 |
| P/F ratio | 0.64 (0.50–0.76) | 90.0% | 37.5% | 41.9% | 88.2% | ≤ 397.5 |
| RSBI | 0.51 (0.38–0.65) | 36.8% | 72.5% | 38.9% | 70.7% | > 51.1 |
| Age | 0.65 (0.52–0.76)* | 82.6% | 43.9% | 45.2% | 81.8% | > 39 years |
AUC area under curve, CI confidence interval, TFC thoracic fluid content, P/F ratio PaO2/fraction of inspired oxygen, RSBI rapid shallow breathing index, PPV positive predictive value, NPV negative predictive value
*Denotes statistical significance