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. 2020 Mar 4;10(3):e032567. doi: 10.1136/bmjopen-2019-032567

Table 3.

Characteristics of the study population stratified according to serum 25(OH)D levels

Total N Deficiency (<25 nmol/L) Insufficiency (25-50 nmol/L) Suboptimal (50–75 nmol/L) Sufficiency (>75 nmol/L) P value
Total population 30 023 1655 (5.5%) 6824 (22.7%) 9467 (31.5%) 12 077 (40.2%)
Sex
 Female 18 688 884 (4.7%) 3920 (21.0%) 5836 (31.2%) 8048 (43.1%) <0.0001
 Male 11 302 770 (6.8%) 2899 (25.7%) 3622 (32.0%) 4011 (35.5%)
Age
 20–29 3099 217 (7.0%) 875 (28.2%) 1054 (34.0%) 953 (30.8%)
 30–39 3721 236 (6.3%) 991 (26.6%) 1242 (33.4%) 1252 (33.7%)
 40–49 3570 227 (6.4%) 954 (26.7%) 1163 (32.6%) 1226 (34.3%) <0.0001
 50–59 4131 214 (5.2%) 995 (24.1%) 1320 (32.0%) 1602 (38.7%)
 60–69 4277 204 (4.8%) 862 (20.1%) 1354 (31.7%) 1857 (43.4%)
 >70 11 225 557 (5.0%) 2147 (19.1%) 3334 (29.7%) 5187 (46.2%)
Medical specialty
 AMU 1690 154 (9.1%) 352 (20.8%) 480 (28.4%) 704 (41.7%)
 BOE 1053 37 (3.5%) 212 (20.1%) 358 (34.0%) 446 (42.4%)
 EMER 1656 122 (7.4%) 392 (23.7%) 460 (27.8%) 682 (41.2%)
 ENDO 1229 42 (3.4%) 221 (18.0%) 417 (33.9%) 549 (44.7%)
 GAST 1574 76 (4.8%) 426 (27.1%) 502 (31.9%) 570 (36.2%) <0.0001
 NEPH 1261 86 (6.8%) 336 (26.6%) 405 (32.1%) 434 (34.4%)
 NEUR 654 33 (5.0%) 120 (18.3%) 209 (32.0%) 292 (44.6%)
 ORTH 1080 72 (6.7%) 215 (19.9%) 376 (34.8%) 417 (38.6%)
 OTHER 14 214 859 (6.0%) 3456 (24.3%) 4462 (31.4%) 5437 (38.3%)
 PRIV 5612 174 (3.1%) 1094 (19.5%) 1798 (32.0%) 2546 (45.4%)
Season of measurement
 Summer (Dec–Feb) 5588 168 (3.0%) 901 (16.1%) 1847 (33.1%) 2672 (47.8%) <0.0001
 Autumn (Mar–May) 8366 266 (3.2%) 1570 (18.7%) 2732 (32.7%) 3798 (45.4%)
 Winter (Jun–Aug) 8320 625 (7.5%) 2324 (27.9%) 2545 (30.6%) 2826 (34.0%)
 Spring (Sep–Nov) 7749 596 (7.7%) 2029 (26.2%) 2343 (30.2%) 2781 (35.9%)
Year of measurement
 2014 8063 277 (3.4%) 1794 (22.2%) 2662 (33.0%) 3330 (41.3%) <0.0001
 2015 7620 310 (4.1%) 1669 (21.9%) 2530 (33.2%) 3111 (40.8%)
 2016 7401 523 (7.1%) 1700 (23.0%) 2267 (30.6%) 2911 (39.3%)
 2017 6939 545 (7.9%) 1661 (23.9%) 2008 (28.9%) 2725 (39.3%)
Vitamin D supplementation
 Yes 2588 63 (2.4%) 294 (11.4%) 786 (30.4%) 1445 (55.8%) <0.0001
 No information 27 435 1592 (5.8%) 6530 (23.8%) 8681 (31.6%) 10 632 (38.8%)

Specialties with <1000 patients (except for NEUR) were placed into OTHER for analysis.

AMU, acute medical unit; BOE, breast/oncology/endocrine surgery; EMER, emergency; ENDO, endocrinology; GAST, gastroenterology; NEPH, nephrology; NEUR, neurology; ORTH, orthopaedic; PRIV, private.