Table 1.

Summary of Human iPSC Lines

Name	Donor Identity	Genotype	Donor Age	Donor Gender	Donor Ancestry
C1	healthy control 1	wild type	30 years	male	Japanese
C2	healthy sibling of P1	heterozygous recessive PIEZO2 mutation c.4723C>T	21 years	female	Bangladeshi
P1	PIEZO2 patient 1	compound heterozygous PIEZO2 mutations c.4723C>T and c.5053C>T	19 years	female	Japanese/European
P2	PIEZO2 patient 2	compound heterozygous PIEZO2 mutations c.5054G>C and c.5053C>T	10 years	female	Bangladeshi
P2C	PIEZO2 patient 2	CRISPR-Cas9-mediated PIEZO2 correction in patient 2 iPSCs	see P2
KO	healthy control 1	CRISPR-Cas9-mediated PIEZO2 knockout in control 1 iPSCs	see C1