TABLE 1.

Computational performance for a typical execution of each LDlinkR function.

LDlinkR function	Number of variants queried	Min. execution time (s)	Median execution time (s)	Estimated number of executions per second	Memory allocated by R (kb)	Total number of iterations
LDhap	3	0.63	0.70	1.41	135	10
LDmatrix	3	0.93	1.09	0.63	118	10
LDpair	2	0.80	0.94	1.07	202	9
LDpop	2	0.72	0.77	1.29	191	10
LDproxy	1	9.10	9.91	0.09	1089	9
LDproxy_batch	2	18.37	20.82	0.05	1633	10
SNPchip	3	0.25	0.28	3.57	194	10
SNPclip	3	0.34	0.39	2.44	119	10