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Number of self-administered cocaine doses as a function of cocaine dose and 0.072 mg/kg hypocretin-1 administration in 5 female rhesus monkeys. Left Panel: Chain Schedule. Responding was maintained under a Fixed interval 1 min; Fixed ratio 10 chain schedule [FI 1-min (FR10:S)] with a maximum of 15 drug infusions. Right Panel: Choice Schedule. There were 15 discrete choice trials with cocaine as one option and 5 M&M® candies as the other option.
