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. 2020 Mar 6;20:181. doi: 10.1186/s12913-020-5038-5

Table 2.

Unadjusted and adjusted Cox models with gamma frailty (total number of events: 469) on mortality in 6872 hospital admissions. The HR of SIPI (> 50 vs ≤50) was estimated separately within 2 time-intervals: before and after day 10 since admission. The effect of SIPI as a continuous variable estimated on a separate multivariable model is also reported

Factors Unadjusted (N = 6872) Adjusted (N = 6872)
HR (95% CI) Pvalue HR (95% CI) Pvalue
Age, per 10 years 1.483 (1.363;1.613) < 0.001 1.233 (1.127;1.350) < 0.001
Gender, Male vs Female 1.050 (0.875;1.260) 0.640 1.266 (1.051;1.527) 0.013
Ward, Medium Intensity vs Low 1.612 (1.333;1.949) < 0.001 1.638 (1.348;1.991) < 0.001
Access, Emergency vs Ordinary 5.037 (2.086;12.160) < 0.001 2.732 (1.125;6.637) 0.026
CCI index, 1 vs 0 1.609 (1.238;2.091) < 0.001 1.606 (1.235;2.089) < 0.001
CCI index, ≥2 vs 0 1.654 (1.252;2.186) < 0.001 1.258 (0.950;1.665) 0.110
SIPI > 50, vs ≤50 at ≤10 days since admission 7.907 (5.450;11.473) < 0.001 6.576 (4.496;9.617) < 0.001
SIPI > 50, vs ≤50 at > 10 days since admission 2.868 (2.048;4.016) < 0.001 2.583 (1.831;3.644) < 0.001
SIPI, per 10 points in the continuous SIPI score at ≤10 days since admission 1.634 (1.526;1.749) < 0.001 1.633 (1.519;1.756) a < 0.001a
SIPI, per 10 points in the continuous SIPI score at > 10 days since admission 1.260 (1.183;1.341) < 0.001 1.255 (1.176;1.339) a < 0.001a

aestimated on a separate multivariable model with the same covariates (regression coefficients not shown)

HR hazard ratio, CI confidence interval, CCI Charlson Comorbidity Index, SIPI Informative System of Nursing Performance