Table 3.

Selected groups of significant GO terms overrepresented in genes correlated with age in female and male

Group	Term_female	P value_F	Term_male	P value_M
Immunity	immune response	2.16E-04	negative regulation of immune system process	1.25E-02
	regulation of immune system process	2.58E-04
	regulation of production of molecular mediator of immune response	7.18E-03
	positive regulation of cytokine production involved in immune response	1.67E-02
	leukocyte mediated immunity	2.98E-02
	immune system process	3.53E-02
	activation of immune response	3.67E-02
	regulation of innate immune response	4.00E-02
	immunoglobulin secretion	4.47E-02
	negative regulation of immune response	4.80E-02
Inflammation	positive regulation of inflammatory response	6.21E-03	acute inflammatory response	1.69E-02
	regulation of inflammatory response	6.90E-03
	acute inflammatory response	1.12E-02
ROS	regulation of reactive oxygen species biosynthetic process	5.79E-04	positive regulation of reactive oxygen species metabolic process	2.63E-03
	positive regulation of reactive oxygen species metabolic process	2.72E-03	regulation of reactive oxygen species biosynthetic process	6.00E-03
	response to oxidative stress	2.22E-02	response to oxidative stress	3.94E-02
	intrinsic apoptotic signaling pathway in response to oxidative stress	3.64E-02
Integrin-associated terms	integrin-mediated signaling pathway	1.67E-05	integrin-mediated signaling pathway	2.72E-04
	integrin binding	7.38E-03	cell adhesion mediated by integrin	3.53E-02
			integrin binding	2.83E-04