Table 1.
Experimental Groups and Measurements
| Animal group | Hindlimb side | Name | Cage condition | Tibial compression | μCT | Serum collection |
|---|---|---|---|---|---|---|
| 1 (n = 10) | Left | Control − TC | Normal ambulation | No | Days 0, 11, 21 | None |
| Right | Control + TC | Normal ambulation | Yes (4 d/wk) | Days 0, 11, 21 | ||
| 2 (n = 15) | Left | HLS − TC | Hindlimb suspension | No | Days 0, 11, 21 | Days 11, 21 |
| Right | HLS + TC | Hindlimb suspension | Yes (4 d/wk) | Days 0, 11, 21 | ||
| 3 (n = 10) | Left/right | HLS control | Hindlimb suspension | No | None | Days 11, 21 |
Control = normal cage activity; HLS = hindlimb suspension; TC = tibial compression.