Table 2. Associations between flavivirus serology and microcephaly.
Prevalence of anti-ZIKV antibody responses as measured by FRNT 90 assay and IgM ELISA is shown for cases and controls. Odds ratios, 95% confidence intervals and p value for the association with microcephaly are shown.
| Seropositivity
n/N (%) |
Crude OR (95% CI) | P | ||
|---|---|---|---|---|
| ZIKV NS1 IgM assay | Controls | 21/864 (2.4%) | 1 | |
| Cases | 2/94 (2.1%) | 0.87 (0.20, 3.78) | 0.86 | |
| ZIKV FRNT90 assay | Controls | 61/755 (8.1%) | 1 | |
| Cases | 7/71 (9.7%) | 1.24 (0.55, 2.83) | 0.60 |