Table 5. CDC-recommended adult immunization schedule after splenectomy.

CDC: Centers for Disease Control and Prevention; IM: intramuscular

Recommended vaccine	Dose of the vaccine	Route of administration	Time of administration
In-hospital protocol
Pneumococcal 13-valent conjugate (PCV13: Prevnar 13)	0.5 mL	IM	On the day of discharge or day 14, whichever comes first
Haemophilus influenza type b vaccine (Hib: ActHIB)	0.5 mL	IM	On the day of discharge or day 14, whichever comes first
Meningococcal vaccine (Menactra)	0.5 mL	IM	On the day of discharge or day 14, whichever comes first
Meningococcal serogroup B (Bexsero)	0.5 mL	IM	On the day of discharge or day 14, whichever comes first
Short-term follow-up
Pneumococcal polysaccharide (PPSV23: Pneumovax 23)	0.5 mL	IM	Two months after the initial vaccination
Meningococcal vaccine	0.5 mL	IM	Two months after the initial vaccination
Meningococcal serogroup B	0.5 mL	IM	Two months after the initial vaccination
Long-term follow-up
Pneumococcal polysaccharide	0.5 mL	IM	5 years after the first dose
Meningococcal vaccine	0.5 mL	IM	Every 5 years
Seasonal influenza vaccine	-	-	Annually