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. 2020 Mar 6;17(3):e1003053. doi: 10.1371/journal.pmed.1003053

Table 1. Summary differences in glycaemic control and cardiometabolic risk factors between intervention and control groups from trials of increasing fibre intakes.

Outcome Trials Participants (I/C) Initial I2 MD (95% CI)
HbA1c (mmol/mol) 33 815/738 98.7% −2.00 (−3.30 to −0.71)
Fasting plasma glucose (mmol/L) 34 936/871 99.1% −0.56 (−0.73 to −0.38)
Total cholesterol (mmol/L) 27 662/605 98.0% −0.34 (−0.46 to −0.22)
LDL cholesterol (mmol/L) 21 559/512 96.2% −0.17 (−0.27 to −0.08)
HDL cholesterol (mmol/L) 25 722/666 96.7% 0.04 (0.01–0.07)
Triglycerides (mmol/L) 28 760/708 97.7% −0.16 (−0.23 to −0.09)
Body weight (kg) 18 455/422 98.2% −0.56 (−0.98 to −0.13)
BMI (kg/m2) 14 382/381 97.4% −0.36 (−0.55 to −0.16)
Waist circumference (cm) 8 178/171 97.4% −1.42 (−2.63 to −0.21)
Systolic blood pressure (mmHg) 12 325/295 98.6% −1.86 (−4.85 to 1.12)
Diastolic blood pressure (mmHg) 12 325/295 97.1% −1.19 (−2.87 to 0.49)
C-reactive protein (SMD) 7 216/217 96.9% −2.80 (−4.52 to −1.09)
Fasting plasma insulin (SMD) 19 489/458 96.4% −2.03 (−2.92 to −1.13)
HOMA IR (mg/dL) 9 292/289 99.7% −1.24 (−1.72 to −0.76)

Abbreviations: BMI, Body Mass Index; HDL, high-density lipoprotein; HOMA IR, homeostatic model assessment of insulin resistance; I/C, intervention/control; LDL, low-density lipoprotein; SMD, standardised mean difference