Table 2. Multivariate cox proportional hazards analysis of the influence of baseline characteristics on PFS and OS (full analysis set).
| Progression Free Survival | Overall Survival | |||||
|---|---|---|---|---|---|---|
| Covariate | HR | 95% CI | p | HR | 95% CI | p |
| NLR (> 5 versus ≤ 5) | 1.4 | 0.9,2.2 | 0.101 | 1.6 | 1.0, 2.7 | 0.052 |
| WHO PS (≥ 1 versus 0) | 1.6 | 1.1, 2.4 | 0.013 | 1.8 | 1.1, 2.8 | 0.011 |
| Metastatic liver disease (yes versus no) | 1.5 | 1.0, 2.4 | 0.079 | 1.4 | 0.8, 2.4 | 0.206 |
| Number of metastatic sites (> 3 versus ≤ 3) | 1.0 | 0.5, 2.0 | 0.886 | 1.5 | 0.8, 3.1 | 0.219 |
| Metastatic liver disease with no other sites (yes versus no) | 1.0 | 0.6, 1.7 | 0.916 | 0.8 | 0.4, 1.5 | 0.440 |