Fig 6. Conduction velocity studies on a cardiac strand and the effect of gap-junction coupling for the Cx43-Cx45 channel with non-symmetric conductance distribution: (left) instantaneous conductance case, (right) steady-state conductance case.

Black color denotes voltage-independent models, red and blue colors denote voltage-dependent models. Predictions from gap-junction voltage-independent models CM clamped, and LHM were insensitive to the direction of wave propagation, whereas voltage-dependent models resulted in CVs that strongly depended on the direction of wave propagation for the steady-state conductance case.