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. 2020 Mar 3;2020(3):CD001838. doi: 10.1002/14651858.CD001838.pub6

Comparison 2. IUI versus TI or expectant management both in stimulated cycle.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Live birth rate per couple (all cycles) 2 208 Odds Ratio (M‐H, Fixed, 95% CI) 1.59 [0.88, 2.88]
1.1 Gonadotropins 2 208 Odds Ratio (M‐H, Fixed, 95% CI) 1.59 [0.88, 2.88]
2 Multiple pregnancy rate per couple 4 316 Odds Ratio (M‐H, Fixed, 95% CI) 1.46 [0.55, 3.87]
2.1 Clomiphene Citrate 1 40 Odds Ratio (M‐H, Fixed, 95% CI) 0.43 [0.02, 11.18]
2.2 Gonadotropins 2 208 Odds Ratio (M‐H, Fixed, 95% CI) 1.61 [0.44, 5.89]
2.3 Clomiphene Citrate and Gonadotropins 1 68 Odds Ratio (M‐H, Fixed, 95% CI) 1.88 [0.32, 11.00]
3 Pregnancy rate per couple (all cycles) 6 517 Odds Ratio (M‐H, Fixed, 95% CI) 1.69 [1.14, 2.53]
3.1 Clomiphene Citrate 1 40 Odds Ratio (M‐H, Fixed, 95% CI) 0.30 [0.03, 2.93]
3.2 Gonadotropins 4 319 Odds Ratio (M‐H, Fixed, 95% CI) 1.68 [1.03, 2.75]
3.3 Clomiphene Citrate and Gonadotropins 1 68 Odds Ratio (M‐H, Fixed, 95% CI) 2.62 [0.98, 6.98]
3.4 Clomiphene citrate OR Gonadotropins 1 90 Odds Ratio (M‐H, Fixed, 95% CI) 1.72 [0.50, 5.89]
4 Moderate or severe ovarian hyperstimulation syndrome rate per woman 1   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected
4.1 Clomiphene Citrate and Gonadotropins 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Miscarriage rate per couple 2 208 Odds Ratio (M‐H, Fixed, 95% CI) 1.66 [0.56, 4.88]
5.1 Gonadotropins 2 208 Odds Ratio (M‐H, Fixed, 95% CI) 1.66 [0.56, 4.88]
6 Ectopic pregnancy rate per couple 1   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1 Gonadotropins 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]