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. 2020 Mar 3;2020(3):CD001838. doi: 10.1002/14651858.CD001838.pub6

Comparison 3. IUI in stimulated cycle versus TI or expectant management in natural cycle.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Live birth rate per couple (all cycles) 2   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected
1.1 Clomiphene Citrate or Letrozole 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
1.2 Clomiphene Citrate or Gonadotropins 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2 Multiple pregnancy rate per couple 2 454 Odds Ratio (M‐H, Fixed, 95% CI) 3.01 [0.47, 19.28]
2.1 Clomiphene Citrate or Letrozole 1 201 Odds Ratio (M‐H, Fixed, 95% CI) 5.05 [0.24, 106.53]
2.2 Clomiphene Citrate or Gonadotropins 1 253 Odds Ratio (M‐H, Fixed, 95% CI) 2.0 [0.18, 22.34]
3 Pregnancy rate per couple (all cycles) 3   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected
3.1 Clomiphene Citrate 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 Clomiphene Citrate or Letrozole 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.3 Clomiphene Citrate or Gonadotropins 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Miscarriage rate per couple 2 454 Odds Ratio (M‐H, Fixed, 95% CI) 2.87 [1.18, 7.01]
4.1 Clomiphene Citrate or Letrozole 1 201 Odds Ratio (M‐H, Fixed, 95% CI) 6.25 [0.74, 52.91]
4.2 Clomiphene Citrate or Gonadotropins 1 253 Odds Ratio (M‐H, Fixed, 95% CI) 2.28 [0.84, 6.20]
5 Ectopic pregnancy rate per couple 1   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected